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PROTOCOLS OPEN
TO ACCRUAL AT UC INFECTIOUS DISEASES CENTER |
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5/18/04, sem |
| IDC STUDY |
POPULATION |
SHORT
TITLE |
INVESTIGATOR |
STUDY NURSE |
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COHORT/PATHOGENSIS
STUDIES |
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| A5001 |
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ACTG Longitudinal
Linked Randomized Linked Randomized Trials (ALLRT) |
Feinberg |
Daria/All Nurses |
| CD40 |
T-cell >100 |
Effects of CD40
Ligand trimer on the immune response in HIV+ pts. |
Subauste |
Hinds |
| SACS |
All IDC pts |
Screening for AIDS
Clinical Studies |
Fichtenbaum |
Hinds |
| IDC 12 |
CD4 >100 VL
>10,000 |
Use of Co-receptors
for HIV in viral quasispecies |
Nelson |
Canaan |
| IDC 13 |
ART
Naïve Pt starting HAART |
Mechanisms of
Defective Expression of CD40 Ligand in HIV Infection |
Chougnet |
Hinds |
| A5128 |
All ACTG patients |
Informed
Consent to use stored Human Biological Materials (HBM) for unspecified
anlyses |
Feinberg |
Daria/All Nurses |
| IDC 27 |
ART Naïve Pt starting
HAART |
The Prevalance of Elevated Blood
Pressures in HIV Infected Persons on ARTl Therapy |
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ANTIRETROVIRAL TREATMENT NAIVE
STUDIES |
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ANTIRETROVIRAL TREATMENT EXPEREINCED
STUDIES |
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| ACTG 5126 |
RTV enhanced PI
subjects |
Study using TDM to
determine appropriate dose for Ritonavir ro PI enhancment |
Feinberg |
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| ACTG 5146 |
Subjects
responding to salvage therapy |
Randomized
controlled trial evaluating the impact of TDM on virologic response to a
salvage regimen |
Feinberg |
Saemann |
| A4301014 |
Dosage Switch of
Nelfinavir |
An
open-label Study to Assess the Relative Exposure of 250-mg VIRACEPT and
625-mg Nelfinavir Mesylate Tablets at Steady State.” |
Feinberg |
Hyc/Canaan |
| BIPI 1182.17 |
Rollover for patients
on 1182.12 |
Open
Label rollover trial assessing the tolerability of Tipranavir and Ritonavir
in HIV infected subjects |
Feinberg |
Saemann/Baer |
| BMS A424-100 |
Switch from LPV/RTV to ATZ/RTV |
Open
label Study evaluating lipids when switching to ATZ/RTV from LPV/RTV in
subjects who have achieved virologic suppression |
Feinberg |
Canaan/Hyc |
| TMC114-C202 |
3 class expereinced
patients |
Dose-response of TMC114-RTV in
3-class-expereinced, Multi PI-Experienced HIV-1 Infected Subjects. |
Feinberg |
Canaan |
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METABOLIC COMPLICATION STUDIES |
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| ACTG 5186 |
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Combination therapy with Fish
Oil Supplement and Fenofibrate on TG levels in pateitns on HAART who are not
responding to either Fish Oil or Fenofibrate alone. |
Fichtenbaum |
Hyc/Canaan |
| Solvay
S1752101 |
HAART
related nausea and vomiting |
Double Blinded
pilot study of oral Dronabinol versus Placebo for the prevention of HAART
related nausea and vomiting. |
Feinberg |
Saemann/Canaan |
| IDC 17 |
20 mother/infant
pairs |
Influence
of HIV Maternal Environment on the Functions of Antigen Presenting Cells |
Chougnet |
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OPPORTUNISTIC
INFECTION/CO-INFECTION STUDIES |
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| A5030 |
CD4 <100 |
Valganciclovir
for CMV viremia |
Feinberg |
Baer/Saemann |
| A5127 |
Hepatitis B + HIV |
Lamivudine-resistant
Hepatitis B virus in Subjects who are co-infected with HIV |
Sherman |
Daria |
| VER002-11 |
Candidiasis |
IV
anidulafungin as Tx for fluconazole-refractory mucosal candidiasis |
Fichtenbaum |
Canaan |
| Hepatitis A |
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The
Effect of HAART and Immune Reconstitution on the Efficacy of an Inactivated
Hepatitis A Vaccine |
Sherman |
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For More Information On Specific Trials Call Linda Hinds at (513) 584-6614 |
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